Health & Medication Exclusion Criteria

You will not be eligible to take part in the PREDICT 2 study if you:

  • Have a Body Mass Index below 16.5 or above 49.9 kg/m2.
  • Have ongoing, active inflammatory disease or condition (e.g. Rheumatoid arthritis, systemic lupus erythematosus, polymyalgia and other connective tissue diseases).
  • Have active cancer or have had cancer in the last two years, excluding skin cancer.
  • Have been diagnosed with Inflammatory Bowel Disease (ulcerative colitis and Crohn’s disease) or Celiac disease (gluten allergy), or any other long term gastrointestinal disorder that would prevent you from safely eating normal US food. Irritable Bowel Syndrome is not an exclusion.
  • Have had bariatric or other major gastrointestinal surgery.
  • Have been medically advised that eating high fat meals over a period of a few days might be dangerous.
  • Currently suffer from severe anemia or jaundice.
  • Have taken any of the following medications in the last three months: immunosuppressants (including oral steroids) or antiretroviral therapies or antibiotics.
  • Have used any steatogenic medications (amiodarone or methotrexate) or insulin in the last three months and are also diagnosed with non-alcoholic fatty liver disease
  • Have an ongoing current illness (e.g. hepatitis c, influenza).
  • Are using medications to manage stomach acid called proton pump inhibitors (such as omeprazole, pantoprazol, Prevacid, Nexium, Prilosec) unless you are safely able to stop two weeks before the start of the study and abstain from use during the study.
  • Have type 1 diabetes mellitus.
  • Are taking medications for type 2 diabetes mellitus containing insulin or sulfonyureas (such as Diamicron (Gliclazide), Diamicron MR (Gliclazide), Amaryl (Glimepiride), Daonil (Gilbenclamide or Glyburide), Gibenese (Glipizide), Minodiab (Glipizide), Tolbutamide (Tolbutamide)).For clarity, use of metformin or gliptin-containing medication for treatment of type 2 diabetes is not an exclusion.If you have been diagnosed with fatty liver disease then you may participate even if you are taking medications for type 2 diabetes.
  • If you are diagnosed with type 2 diabetes mellitus and not on medications you will need to report to us that you have a fasting glucose level of <216 mg/dL.
  • Started antidepressant medication within the last 3 months, or are currently suffering from acute clinically diagnosed depression which is not well controlled.
  • Have had a heart attack (myocardial infarction) or stroke in the last 6 months.
  • Are pregnant or breastfeeding, have given birth in the last three months, or are planning to be pregnant in the next 3 months.
  • Diagnosed with an eating disorder (e.g. anorexia nervosa or bulimia nervosa)
  • Have a known allergy to adhesives like that used to affix the continuous glucose monitor (Blood Sugar Sensor).